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Ananya Vinayak
Advisor: Dr. Onn Brandman
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Brandman Lab finds new functions and molecular mechanism for CAT tails in protein quality control
Jan 8, 2026Recent research from the Brandman Lab (Danish Khan, Ananya Vinayak, Cole Sitron, and Onn Brandman) reveals a new force-based mechanism for quality control of stalled ribosomes. CAT tailing is a conserved, non-templated process that extends stalled nascent polypeptide chains while they are still attached to the large ribosomal subunit.