Personal Reviews

Berg, P., 2003. Moments of Discovery: My Favorite Experiments. J.Biol.Chem. 278: 40417-24
Berg, P. 2008. Moments of discovery Annual Review of Biochemistry 77: 15-44
Berg, P. 1981. Nobel Prize paper Dissections and Reconstructions of Genes and Chromosomes Science 213: 246

Public Policy papers

Berg, P., Baltimore, D., Boyer, H., Cohen, S., Davis, R., Hogness, D., Nathans, D., Roblin, R., Watson, J., Weissman, S.,
Zinder, N. 1974. Potential biohazards of recombinant DNA molecules. Science 185: 303.

Berg, P., Baltimore, D., Brenner, S., Roblin, RO., Singer, M. 1975. Asilomar conference on recombinant DNA molecules. Science 188: 991.

Berg, P., Singer, M. 1995. The recombinant DNA controversy: Twenty years later. PNAS 92,  9011-9013.

Berg, P., 2004. Asilomar and Recombinant DNA. website: http://www.nobel.se/chemistry/articles   (August 26, 2004)

Berg, P., 1999. Scientists and the Public: An Ambivalent Partnership Useful Knowledge, Amer.  Phil. Soc. 1999; 71-78:

Berg, P, 2006. Brilliant Science, Dark Politics, Uncertain Law. Jurimetrics 46

Berg P, 2006. Origins of the human genome project: why sequence the human genome when 96% of it is junk? Am. J. Hum. Genet. 79: 4: 603-5


• Singer, M., Berg, P. 1990. Genes and Genomes: A Changing Perspective. Mill Valley (CA) 
  University Science Books
• Berg, P., Singer, M. 1992. Dealing with Genes: The Language of Heredity. Mill Valley (CA): 
  University Science Books
• Singer, M., Berg, P. 1997. Exploring Genetic Mechanisms. Sausalito, University Science Books.
  Berg, P, Singer, M. 2003 George Beadle: An Uncommon Farmer. Cold Spring Harbor Laboratory 
  Press (NY)

Significant Publications from the BERG LAB

  1. Chamberlin, M. Berg, P. 1962. Deoxyribonucleic acid-directed synthesis of ribonucleic acid by an enzyme from Escherichia coli. PNAS 48: 81.

  2. Wood, WB. Berg, P. 1962. The effect of enzymatically synthesized ribonucleic acid on amino acid incorporation by a soluble protein-ribosome system from Escherichia coli. PNAS 48: 94.

  3. Norris, AT., Berg P. 1964. Baldwin, AN., Berg, P. 1966/ Purification and properties of isoleucyl ribonucleic acid synthetase from E. coli. J. Biol. Chem. 241: 831. Mechanism of aminoacytl RNA synthesis: Studies with isolated aminoacyl adenylate complexes of isoleucyl RNA synthetase. PNAS 52: 330.

  4. Carbon, J., Berg, P., Yanofsky, C. 1966. Missense suppression due to a genetically altered tRNA. Cold Spring Harbor Symp. 31: 487.

  5. Soll, L., Berg, P. 1969. Recessive lethals: A new class of nonsense suppressors in Escherichia coli . PNAS 63: 392. Soll, L., Berg, P. 1969 Recessive lethal nonsense suppressor in Escherichia coli, which inserts glutamine. Nature 233: 1340.

  6. Jackson, DA., Symons, RH., Berg, P. 1972. Biochemical method for inserting new genetic information into DNA of Simian Virus 40: Circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli. PNAS 69: 2904.

  7. Mertz, J., Carbon, J., Herzberg, M., Davis, R., Berg, P. 1974. Isolation and characterization of individual clones of Simian Virus 40 mutants containing deletions, duplications and insertions in their DNA. Cold Spring Harbor Symp. Quant. Biol. 39: 69 and in Viral Transformation and Endogenous Viruses (Kaplan, A.S., Ed.). New York: Academic Press

  8. Carbon, J., Shenk, TE., Berg, P. 1975. Biochemical procedure for production of small deletions in simian virus 40 DNA. PNAS 72: 1392. Shenk, TE., Carbon, J., Berg, P. 1976. Construction and analysis of viable deletion mutants of simian virus 40. J. Virol. 18: 664.

  9. Mulligan, RC., Howard, BH. , Berg, P. 1979 Synthesis of rabbit b-globin recombinant genome. Nature 277, 108-114.

  10. Goff, SP, Berg, P. 1979. Construction, propagation and expression of simian virus 40 recombinant genomes containing the Escherichia coli gene for thymidine kinase and a Saccharomyces cerevisae gene for tyrosine transfer RNA. J. Mol. Biol. 133, 359.

  11. Mulligan, RC. , Berg, P. 1980. Expression of a bacterial gene in mammalian cells. Science 209, 1422-1427. Mulligan, RC. , Berg, P. 1981. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyl transferase. PNAS 78, 2072-2076.

  12. Okayama, H., Berg, P. 1982. High efficiency cloning of full-length cDNA. Molec. and Cell. Biol. 2, 161-170. Okayama, H., Berg, P. 1983. A cDNA-cloning vector that permits expression of cDNA inserts in mammalian cells. Mol. & Cell. Biol. 3, 2, 280-289.

  13. Fromm, M., Berg, P. 1983. SV40 early and late region promoter function are enhanced by the 72 base pair repeat inserted at distant locations and inverted orientations. Mol. and Cell. Biol. 3, 991-999.

  14. Jessberger, R., Berg, P.1991. Repair of deletions and double strand gaps by homologous recombination in a mammalian in vitro system. Molec. and Cell. Biol. 11: 445-457.

  15. Donoho, G., Jasin, M., Berg, P.1998. Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Molec & Cell Biology 18: 4070. 

Personal story

An interview with Paul Berg

Protein Synthesis film

P. Berg & Nate Oliveira film 

Web site for Berg description of first recombinant DNA

Paul Berg on Science Policy

An Oral History